Limited Competition: Revision Applications of Existing NIH Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) Grants (P30 Clinical Trial Not Allowed) | PAR 24 080

Opportunity Information: Apply for PAR 24 080

This funding opportunity (PAR-24-080) is a limited-competition NIH grant for institutions that already hold an NIH-funded Center for AIDS Research (CFAR) or Developmental CFAR (D-CFAR) award and want to submit a revision application to expand what their existing center can do. The revision is meant to strengthen and broaden CFAR and D-CFAR infrastructure so these centers can provide additional support for outreach and research focused on HIV and HIV-related health disparities, both within the United States and in global contexts where appropriate. It is not a standalone new center award; it is specifically a request to modify and enhance an existing CFAR or D-CFAR grant through a revision, building on the current center structure and capabilities.

A central theme of the NOFO is workforce development and equity in the research pipeline. NIH is explicitly aiming to diversify and support the next generation of HIV/AIDS investigators by creating or expanding center-based resources that help recruit, engage, train, and mentor investigators into high-priority HIV/AIDS research areas. In practical terms, that typically means the revision should propose added capacity that makes it easier for emerging investigators to enter the field, access expertise and shared resources, connect with communities, and develop competitive research trajectories that address urgent HIV science needs and persistent disparities.

The opportunity is categorized as a discretionary grant in the health area and uses the P30 center mechanism, with clinical trials not allowed under this particular announcement. The focus is therefore on center infrastructure, coordination, and support activities rather than running clinical trials as part of the award. The ceiling amount listed for an award is up to $1,500,000, indicating NIH is willing to support substantial expansions of center capabilities when the proposed revision is well-justified, feasible, and clearly aligned with the goals of strengthening outreach, disparities-focused research support, and investigator development.

Eligibility is restricted. Because it is a limited competition, the main intent is that only currently funded NIH CFAR and D-CFAR awardees submit revision applications. Foreign organizations (non-U.S. entities) are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. At the same time, foreign components are allowed as defined by the NIH Grants Policy Statement, meaning a U.S.-based applicant can include certain international elements or collaborations when they meet NIH definitions and requirements, but the applicant organization itself must be eligible and U.S.-based. The source data also lists "Small businesses" under eligible applicants, but given the limited-competition nature and the CFAR/D-CFAR P30 context, the practical target audience is existing NIH CFAR or D-CFAR centers submitting revisions through their current awards.

Key administrative details include the funding opportunity number PAR-24-080, the NIH as the issuing agency, and an original closing date of 2025-10-09. The CFDA number associated with this program area is 93.855. Overall, the NOFO is designed to leverage the national CFAR network by helping current centers extend their infrastructure and outreach reach, strengthen HIV disparities research capacity, and build a stronger, more diverse pipeline of HIV investigators through structured engagement and mentorship tied to high-priority HIV/AIDS research.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: Revision Applications of Existing NIH Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) Grants (P30 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855.
• This funding opportunity was created on 2023-12-20.
• Applicants must submit their applications by 2025-10-09. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
• Eligible applicants include: Small businesses.

Apply for PAR 24 080

[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal: