Opportunity Information: Apply for CDC RFA GH20 2028

The grant opportunity titled "Coordination and Strengthening of the Kingdom of Eswatini Ministry of Health's HIV and TB Programs under the President's Emergency Plan for AIDS Relief (PEPFAR)" is a CDC-funded cooperative agreement designed to strengthen how Eswatini's Ministry of Health plans, leads, and coordinates its national HIV and TB/HIV response. The focus is not simply on delivering services in isolation, but on improving the systems that make large-scale HIV and TB programming effective: national and regional coordination, leadership and governance, workforce capacity, data systems, quality improvement, and long-term sustainability. In practical terms, the funding is meant to help the Ministry of Health work more efficiently across national and subnational levels while partnering with other relevant government departments to transfer skills, build institutional capacity, and reinforce program management for sustained epidemic control.

This opportunity is issued by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), under Funding Opportunity Number CDC RFA GH20 2028. It falls under the "Discretionary" opportunity category and uses a "Cooperative Agreement" funding instrument, which typically means CDC expects to have substantial involvement in the work beyond standard grant oversight, such as technical collaboration, joint planning, and ongoing performance monitoring. The funding activity category is Health, and it is associated with CFDA number 93.067, a code commonly tied to global HIV and TB-related public health work.

The program is structured around helping Eswatini's Ministry of Health coordinate the HIV response at both national and subnational levels, with strong integration of TB/HIV efforts. A central theme is strengthening leadership, governance, and coordination mechanisms so that policies, planning, implementation, and accountability function consistently across regions and facilities. The Ministry of Health is expected to collaborate with other government entities to ensure skills transfer and capacity building are embedded, rather than relying indefinitely on external support. This approach aligns with PEPFAR goals that emphasize country ownership, strong public-sector management, and durable systems that can sustain results over time.

Several technical areas are explicitly highlighted. One major component is Human Resources for Health (HRH), recognizing that achieving and maintaining epidemic control depends heavily on having enough trained personnel, appropriate staffing models, supportive supervision, and the capacity to deploy and retain staff where they are needed most. Another key area is Strategic Information (SI) and Monitoring and Evaluation (M and E), including strengthening processes for data collection, analysis, reporting, and especially data use at every level of the health system, from individual facilities to regional management teams and national leadership. The grant also calls for ongoing quality improvement (QI), signaling an emphasis on continuously identifying gaps in program performance and implementing practical, measurable changes to improve outcomes. Finally, it includes the development and implementation of a sustainability plan, which usually means documenting how the Ministry will maintain core functions, financing approaches, technical capacity, and governance structures over time, even if external funding decreases.

In terms of funding, CDC states it anticipates approximately $5,000,000 in total fiscal year funding for Year 1, contingent on the availability of funds. The listing also notes an "Award Ceiling for Year 1 is 0 (none)," which typically indicates that no formal maximum award amount is being set in the announcement even though an estimated total amount is provided. The expected number of awards is 1, suggesting a single recipient will be selected to carry out the work, consistent with a model where one primary award supports the Ministry of Health's coordination and systems strengthening agenda.

Key dates in the posting show it was created on January 7, 2020, with an original closing date of March 7, 2020. Applications were required to be submitted electronically by 11:59 p.m. Eastern Time on the due date. Eligibility is listed broadly as "Others," with additional eligibility details referenced in the full announcement text, meaning applicants would need to consult the complete NOFO to confirm which organizations could apply and under what conditions.

Overall, the opportunity is best understood as an investment in public-sector capacity and program governance for HIV and TB/HIV in Eswatini under PEPFAR, with CDC collaboration through a cooperative agreement. Rather than focusing on a single intervention, it supports the underlying coordination, workforce, data systems, quality management, and sustainability planning needed to run a high-performing national response and maintain progress toward epidemic control.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Coordination and Strengthening of the Kingdom of Eswatini Ministry of Health's HIV and TB Programs under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Jan 07, 2020.
  • Applicants must submit their applications by Mar 07, 2020 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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