Opportunity Information: Apply for PAR 21 347
The Clinical Research Education and Career Development (CRECD) Program is an NIH Research Education Program (R25) funding opportunity from the National Institute on Minority Health and Health Disparities (NIMHD). It is designed to support structured research education activities that fall within NIH mission areas, with an overall emphasis on strengthening and diversifying the clinical research workforce. In practical terms, the program is meant to build training pipelines and career development pathways that help bring more people from underrepresented backgrounds into clinical and health-related research careers, and to better prepare them with the skills and experiences needed to succeed.
This opportunity specifically supports educational and training-focused programs rather than traditional hypothesis-driven research projects. The FOA calls for creative, well-organized education activities, with the main programmatic emphasis on two core components: Courses for Skills Development and Research Experiences. Courses for Skills Development generally refers to formal training that builds foundational and advanced competencies relevant to clinical research, such as research methods, study design, data management, responsible conduct of research, ethics, and other professional skills that improve readiness for clinical research roles. Research Experiences refers to hands-on opportunities that immerse participants in real research environments, often through mentored experiences that help them apply what they learn, build confidence, and develop a clearer trajectory toward clinical research careers.
A key limitation is embedded directly in the funding opportunity title: "Independent Clinical Trial Not Allowed." That means applicants should not propose an independent clinical trial as part of the R25 program. The intent is education and workforce development, not running a new clinical trial led by the awardee as the primary study. Programs can still include training about clinical trials and may involve research experiences that expose trainees to clinical research settings, but the grant mechanism is not meant to fund the applicant to independently conduct a clinical trial.
Eligibility is broad across U.S.-based organizations that can deliver high-quality research education. Eligible applicant types include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including both 501(c)(3) nonprofits and nonprofits without 501(c)(3) status, as long as they are not institutions of higher education). The FOA also highlights additional eligible applicant categories that are especially aligned with the diversity-focused mission of the program, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). At the same time, the opportunity is clearly limited to domestic applicants and activities: non-U.S. (foreign) institutions are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.
Administratively, this is a discretionary grant opportunity under the NIH umbrella, categorized under Education and Health funding activity areas. The funding opportunity number is PAR 21-347, created on October 19, 2021, with an original closing date of December 15, 2021. The listed award ceiling is $500,000, indicating the maximum award amount expected under the announcement. The CFDA (assistance listing) numbers associated with the program are 93.121, 93.307, and 93.361, which correspond to NIH-related assistance listings and help identify the federal program areas tied to the funding.
Overall, this FOA is aimed at organizations that can demonstrate a strong, well-structured plan to train and mentor participants for clinical research careers, with measurable strategies to enhance diversity in the clinical research workforce. Competitive programs under this announcement would typically be expected to show how their coursework and research experiences will translate into stronger clinical research capacity, improved participant preparedness, and clearer career progression for trainees, while staying within the R25 education-focused scope and avoiding independent clinical trial activities.Apply for PAR 21 347
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Clinical Research Education and Career Development (CRECD) Program (R25-Independent Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.307, 93.361.
- This funding opportunity was created on 2021-10-19.
- Applicants must submit their applications by 2021-12-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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| Funding Opportunity |
|---|
| Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed) Apply for PAR 22 049 Funding Number: PAR 22 049 Agency: National Institutes of Health Category: Education, Health Funding Amount: $250,000 |
| A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials (CUSP2CT; U01 Clinical Trial Optional) Apply for RFA CA 21 063 Funding Number: RFA CA 21 063 Agency: National Institutes of Health Category: Education, Health Funding Amount: $450,000 |
| Clinical Sites for HIV/Cervical Cancer Prevention 'CASCADE' Clinical Trials Network (UG1 Clinical Trial Required) Apply for RFA CA 21 047 Funding Number: RFA CA 21 047 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Coordinating Center for HIV/Cervical Cancer Prevention 'CASCADE' Clinical Trials Network (U24 Clinical Trial Required) Apply for RFA CA 21 045 Funding Number: RFA CA 21 045 Agency: National Institutes of Health Category: Education, Health Funding Amount: $750,000 |
| Research Bases for HIV/Cervical Cancer Prevention 'CASCADE' Clinical Trials Network (UG1 Clinical Trial Required) Apply for RFA CA 21 046 Funding Number: RFA CA 21 046 Agency: National Institutes of Health Category: Education, Health Funding Amount: $400,000 |
| Limited Competition: NIH Health Care Systems Research Collaboratory - Coordinating Center (U24 Clinical Trial Not Allowed) Apply for RFA AT 22 002 Funding Number: RFA AT 22 002 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| HEAL Initiative: Sickle Cell Disease Pain Management Trials Utilizing the Pain Management Effectiveness Research Network Cooperative Agreement (UG3/UH3, Clinical Trial Required) Apply for RFA AT 22 005 Funding Number: RFA AT 22 005 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| HEAL Initiative: Pragmatic and Implementation Studies for the Management of Sickle Cell Disease Pain (UG3/UH3, Clinical Trials Optional) Apply for RFA AT 22 004 Funding Number: RFA AT 22 004 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Modulating Human Microbiome Function to Enhance Immune Responses Against Cancer (R21 Clinical Trial Not Allowed) Apply for PAR 22 062 Funding Number: PAR 22 062 Agency: National Institutes of Health Category: Education, Health Funding Amount: $275,000 |
| Modulating Human Microbiome Function to Enhance Immune Responses Against Cancer (R01 Clinical Trial Not Allowed) Apply for PAR 22 061 Funding Number: PAR 22 061 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Innovative Biospecimen Science Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed) Apply for RFA CA 22 003 Funding Number: RFA CA 22 003 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed) Apply for RFA CA 22 004 Funding Number: RFA CA 22 004 Agency: National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Basic Experimental Studies with Humans Required) Apply for RFA CA 21 062 Funding Number: RFA CA 21 062 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required) Apply for RFA CA 21 061 Funding Number: RFA CA 21 061 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed) Apply for RFA CA 21 060 Funding Number: RFA CA 21 060 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NIH HEAL Initiative: Preventing Opioid Misuse and Co-Occurring Conditions by Intervening on Social Determinants (R01 Clinical Trials Optional) Apply for RFA DA 22 036 Funding Number: RFA DA 22 036 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Drug Discovery For Nervous System Disorders (R21 Clinical Trials Not Allowed) Apply for PAR 22 032 Funding Number: PAR 22 032 Agency: National Institutes of Health Category: Education, Health Funding Amount: $275,000 |
| Toward Translation of Nanotechnology Cancer Interventions (TTNCI) (R01 Clinical Trial Not Allowed) Apply for PAR 22 071 Funding Number: PAR 22 071 Agency: National Institutes of Health Category: Education, Health Funding Amount: $475,000 |
| Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed) Apply for RFA CA 22 001 Funding Number: RFA CA 22 001 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed) Apply for RFA CA 22 002 Funding Number: RFA CA 22 002 Agency: National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
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